The Overseas Highway Is the Main Event
The drive through the Florida Keys turns the journey into part of the vacation, with bridges, turquoise water, seafood towns, state parks, and island stops before reaching Key West.
Follow the Overseas Highway to island views, Key West sunsets, Dry Tortugas day trips, and Florida Keys camping.
Key West is one of the most recognizable road-trip endpoints in the United States, and the drive is a major part of the appeal. Instead of flying directly to the island, a campervan trip lets travelers follow the Florida Keys from the mainland through Key Largo, Islamorada, Marathon, the Seven Mile Bridge, Bahia Honda, Big Pine Key, and finally Key West. The route has the feeling of a true escape: turquoise water on both sides, low bridges, seafood stops, marinas, state parks, and mile markers counting down toward the end of U.S. 1.
Once in Key West, the trip shifts from long scenic driving to island rhythm. Travelers can explore Old Town, walk Duval Street, watch sunset at Mallory Square, visit Fort Zachary Taylor Historic State Park, take a ferry or seaplane to Dry Tortugas National Park, and build in beach, snorkeling, boating, or food-focused days. A campervan makes the broader Florida Keys route easier because the home base travels with you; the important part is reserving appropriate campgrounds and understanding that Key West itself is dense, popular, and not a casual overnight-parking destination.
This destination should be positioned as a planned warm-weather campervan trip rather than a spontaneous beach weekend. Campsites in the Keys can sell out early, driving days should account for traffic and bridge conditions, and travelers should confirm any van-specific, pet, ferry, toll, and campground rules before booking. For renters who plan ahead, Key West gives Glamp Mobile a high-impact destination page: iconic scenery, a famous route, strong winter demand, and a clear reason to choose a comfortable, self-contained campervan over a traditional hotel-only trip.

Best Overall Season: Winter through spring, with careful hurricane-season planning
Spring is quieter and flexible, with cool lake air, reopening patios, early-season biking, and fewer peak-summer crowds. It is a good fit for travelers who want a calmer Burlington trip and do not need every beach or summer event to be in full swing.
Summer brings heat, humidity, strong sun, and the start of the Atlantic hurricane season, but it can still work for travelers who plan around weather, hydration, shade, air conditioning needs, and flexible activity timing. Morning and evening sightseeing often feels better than mid-day wandering.
Fall can offer a slower Keys experience, but it overlaps with hurricane season and some travelers will need extra flexibility. This is best for renters who are comfortable monitoring weather, travel advisories, ferry updates, campground policies, and refund or rescheduling rules.
Winter is one of the strongest seasons for Key West and the Florida Keys. It is a warm escape from northern weather, but that popularity means campgrounds and tours can book far in advance. Plan early, expect higher demand, and keep driving days realistic.

Key West and the Florida Keys are high-demand winter and holiday destinations. Book campgrounds, state park sites, private RV parks, Dry Tortugas transportation, and popular tours well ahead of time. Do not rely on informal overnight parking in Key West.
Off-season travel can be rewarding for flexible renters, but heat, storms, closures, and weather-sensitive ferry or boating plans matter. Build backup days into the itinerary and confirm campground and activity policies close to departure.

Key West is a fit for renters who want a warm-weather campervan route with planned campgrounds, island stops, and a famous finish line.